Lexie is surprised to hear that Izzie has sent Alex divorce papers. Alex insists that what he and have Lexie have isn't a "thing" but Meredith tells him, "You should make it a thing or put a stop to it."
Miranda puts the team through sensitivity training prior to admitting a 700-pound patient with stomach problems. Miranda orders Cristina and Jackson off the case, so they end up with a mother who didn't realize she was having a heart attack. Cristina, who usually can't stand children, stays with the woman's little girl and we realize it reminds her of when she lost her own father at a young age.