Meredith muscles in on a heart operation that Cristina was supposed to do solo. These two do not work and play well together. Cristina takes over the entire operation and later drops the bombshell that Mer's fiancé, Alex, is having an affair with her person, April. Uh oh.
Cristina isn't completely evil in this alternate universe. She tends to Owen after he punches a glass window in a sudden burst of rage. This isn't the first anger episode she's helped him through. She eventually works with Meredith to save Lexie after complications arise. Meredith is getting along better with Cristina, but she can't stand the way her mother tries to make everyone around her feel ordinary. Sound familiar?
The newly-unemployed Mandy Bailey tells a distraught Alex that we create our own destiny. Guess that's why Meredith and Cristina agree to skip a tender moment where someone cries. It may also be the reason why Meredith tells Derek that his nickname around the hospital is McDreary. Things could be different. Derek could just be some guy in a bar and Meredith could just be some girl. Why? Because some things are just meant to be.