McDreamy and Addison clash over their friend’s request for radical surgery. Meredith’s elderly patients restore her belief in true love. George nearly gets crushed by a man who falls five stories. Cristina and Burke have the best date ever. One of Seattle Grace’s surgeons is pregnant!

McDreamy and Addison’s married friends from New York come to Seattle. The wife tested positive for the cancer gene and wants a hysterectomy and radical mastectomy. Her husband is completely against it—he’s still hoping to have kids. Being on opposing sides puts a strain on the Shepherds’ relationship. Everyone is divided over this case.

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