Colin Marlow has a 10-year plan for Seattle Grace. Once word of the plan reaches the others vying to become Chief, they all try to outdo each other. Mark picks Miranda's brain about what the hospital needs for the future, but all she can think about is what’s needed right now. Addison, Burke and Derek are amazed when Sloan wows the board with his "Right Now" plan. Did anyone else notice the daggers shooting out of Bailey’s eyes?
Callie's patient, Cathy, has an incredibly rare disease which turns muscle into bone. She has internal bleeding, likely caused from too many painkillers. She knows she'll die of this disease sooner or later, so she asks what will happen if she refuses surgery. Callie tells her she'll bleed to death. Her daughter, Nina, won't hear of her mother giving up. Sadly, Cathy bleeds out on the operating table. Izzie tries to comfort her daughter by telling her that her mom was worried that she had taken on so much of her disease that she was freezing up, too. If she falls, she won’t break. Think this has anything to do with how Izzie’s feeling after having slept with George?