Arizona crashes just as Callie operates on Derek's hand. Alex needs consent to cut off her leg to save her life. Callie has no choice but to give it to him. Meredith offers to help with her husband's operation. Callie assures her that she's fine. As Meredith watches the rest of the operation from the observation room, she leaves a voicemail message for Cristina. A lot of bad things have happened to her in Seattle, but so many wonderful experiences have shaped her life there as well. Cristina calls back to assure Mer that she will always be her person.
Lots of things are happening as Mark Sloan slips into the coma from which he will never awaken. April stuck around for awhile, but ultimately headed back home. She and Jackson didn't really have a chance to say goodbye. Alex amputates Arizona's leg while Callie completes Derek's surgery. Richard is by Mark's side as he takes one last breath before crashing. We already know what happens after this and we're all still heartbroken by it.