Any Grey’s Anatomy fan can tell you just how intertwined our favorite doctors' love lives have become over the last 11 years. Well, during the "Can We Start Again, Please?” episode, Callie, Alex and Meredith made that “horribly weird” realization for themselves. Check out the clip above to see the hilarious moment when Callie declares they are all related through sex. And then watch the classic Grey’s Anatomy scenes below to see all of the hookups mentioned!
WATCH: Meredith and George Have Sex! (It doesn’t end well.)
WATCH: The Callie & Alex Hookup!
WATCH: Callie Loves George
Click here for even more classic Grey's Anatomy moments. And watch all-new episodes THURSDAYS 8|7c!