Key Moments in Mark's Life

- Mark's friendship with Derek was restored when Mark supported Derek after Meredith's near drowning.

- While living with Lexie, Mark's long-lost daughter showed up on their doorstep out of the blue. She was homeless and needed her dad's help. Of course Mark steps up, but this caused tension between him and Lexie. The stress became too much and they eventually broke up.

- Mark had a one-night stand with Callie Torres which resulted in the birth of Sofia, their daughter.

- After much hesitation, Mark realized Jackson had skillss and decided to teach him the art of plastic surgery. Mark eventually became close to Jackson and even tried to name their team the 'Plastics Posse.'