Aprilâ€™s sisters arrive to help celebrate Aprilâ€™s upcoming nuptials and quickly get on her nerves. Matthew and Jackson are forced to work together when they witness a terrible accident, Callie and Arizona work hard to reestablish their relationship and Cristina is pressured to live stream an upcoming surgery. Meanwhile, a familiar face returns to the hospital.
Ben worries that a casual conversation with Derek could potentially cause issues for Bailey, Cristina turns to Shane as tension grows with Meredith, and Aprilâ€™s upcoming wedding makes for an uncomfortable situation between Jackson and Stephanie. Meanwhile, Meredith plans a Thanksgiving dinner at her house
When an unexpected malpractice suit turns Callie's world upside down, her supportive father (Hector Elizondo) arrives and shares an interesting secret with her. Meanwhile, through flashbacks, we learn some surprising details about Callie and Arizona's marriage.
The issues between Meredith and Cristina hit a boiling point when one of them ultimately betrays the other at the hospital. Derek tells Jackson that he needs to let go and allow the second year doctors to work on his patients, and April and Matthew make a bold decision about their relationship. Meanwhile, Bailey has difficulties with Benâ€™s return.
It's Halloween and the doctors of Grey Sloan Memorial are hit with a barrage of spooky patients, which affects their own plans and puts one doctor's well-being in jeopardy. Meanwhile, Derek collaborates with Ben on a new surgical technique, and Richard angers Bailey when he asks a second year resident to perform his next surgery.
On the day of Aprilâ€™s wedding, the Grey Sloan Memorial doctors are all preoccupied with their own drama. Meredith and Cristina continue to argue about their research and careers, Bailey comes clean to Ben about her feelings regarding him moving back to Seattle, and Shane puts himself in a risky situation. Meanwhile, Derek gets a phone call that will change his life
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