On the heels of their encounter with Ghost Rider and battling the Watchdogs to their highest ranks, the Agents of S.H.I.E.L.D. find themselves in their most mind-bending mission yet. The heroes have been plugged into a virtual reality known as "The Framework," created by Dr. Radcliffe and Fitz. They awake to find themselves in an unrecognizable world – a world in which Hydra reigns supreme. What will become of the team as they make their way through this strange new landscape? What friends and foes will they face? And ultimately, will they ever escape and return to their real lives?
Running out of options, Coulson's only hope at saving his team is to put them in the line of fire.
Coulson and his team race against Hydra to find a man with the ability to freeze objects.
While Coulson tries to learn more about the mysterious writing, Melinda May attacks him.
Coulson and the team are faced with Hydra's security chief -- the beautiful, deadly Bobbi Morse.
While impersonating S.H.I.E.L.D., Hydra orchestrates a devastating attack on the United Nations.
Coulson's etchings lead the team to several murder victims; lies and secrets come to a head.
Coulson and the team face off against Hydra as they try to uncover an ancient secret.
S.H.I.E.L.D. discovers the ancient city but uncovering the secrets may require a major sacrifice.
An explosive confrontation changes everyone's fate; Skye uncovers secrets about her past.
Coulson and the team help Lady Sif, who lost her memory after a fight with a mysterious warrior.
A shocking revelation and an impending decision leaves the team broken.
As stunning revelations are brought to light, war comes to Coulson in a way he did not expect.
After Robert Gonzales takes action, Coulson fights to protect the future of S.H.I.E.L.D.
The story of Melinda's transformation is revealed; Skye learns more about her heritage.
Gonzales and Coulson fight to put aside their differences as they work with an untrustworthy ally.
As tensions rise between S.H.I.E.L.D. and Inhumans, Skye finds herself torn between the groups.
In part one of the season finale, the Inhumans' endgame is revealed.
In part two of the season finale, the Inhumans' endgame is revealed.