In 2005, Cohen moved out to L.A. and within the year signed on with The N network, a programming arm of MTV Networks, as a series regular on the award-winning South of Nowhere. Cohen played the charismatic golden boy "Aiden." The show was produced by the Tom Lynch Company and completed three seasons.
In 2007, Cohen transitioned to film with the lead in Columbia Picture's Boogeyman 2, directed by Jeff Betancourt and written by Brian Sieve. Cohen plays the charming "Henry Porter" in the sequel to Screen Gem's successful 2005 film. Cohen continued to excel in his acting endeavors with numerous guest starring roles and a high profile recurring guest on the CW's Supernatural as young John Winchester (Jeffrey Dean Morgan.)
In 2009, Cohen went on to secure lead roles in several feature films including Chain Letter, written and directed by Deon Taylor, Almont Films' drama The Outside, written and directed by Ari Davis, and Dark House, directed by Darin Scott and written by Darin Scott and Kerry Douglas Dye. Later that year, Cohen joined producer Josh Schwartz (The OC, Gossip Girl, Chuck) for his innovative angst-filled comedy web series Rockville, CA as the sexy bassist/bartender "Syd."
Cohen went on to secure a recurring role in CW's 90210 as "Jeremy" in 2011. In 2015, he landed the role of "Levi Sutter" in a large 4-episode arc on ABC's award-winning drama, How to Get Away with Murder, and reprised his role of young John Winchester on the CW's Supernatural, bringing the span of this role to 8 years.
Most recently, Cohen is proud to join the prestigious cast of ABC's General Hospital where he made his 2016 debut as Dr. Griffin Munro.