Martha Plimpton, David Arquette, Tom Bergeron and Sherri Shepherd make up the celebrity panel. In this episode the panel is faced with finding out whom the very first guest was on "The Oprah Winfrey Show," a contestant who lost 365 pounds by walking, a contestant who only ate Starbucks for 365 days, someone who can extract venom from snakes and a professional butt model.
Mel Brooks; Joel McHale; Bill Hader; Natasha Leggero
Octavia Spencer; Dermot Mulroney; Nikki Glaser; Gabby Douglas
Nikki Glaser, Mel Brooks, Cloris Leachman, Michaela Watkins